The international GEOTRACES program was developed to enhance knowledge about the distribution of trace elements and their isotopes (TEIs) in the ocean and to reduce the uncertainty about their sources, sinks, and internal cycling. Recognizing the importance of intercalibration from the outset, GEOTRACES implemented intercalibration efforts early in the program, and consensus materials were generated that included the full range of TEIs dissolved in seawater, in suspended particles, and from aerosols. The GEOTRACES section cruises include “crossover station(s)” that are occupied by two or more sections and whereby all aspects of sample collection, preservation, and processing can be compared and intercalibrated. Once datasets are generated, an international intercalibration committee reviews intercalibration reports and works with the community to address issues and provide intercalibrated data for intermediate data products. This process has resulted in a highly cooperative community that shares advances in protocols to strengthen capacity building and GEOTRACES outcomes, including an unprecedented oceanic atlas of TEIs, with data quality that is state-of-the-art. This article outlines the development and implementation of the successful GEOTRACES intercalibration process.