The Tonga-Lau-Fiji region is important to study plate-plume and subduction-ridge interactions, but its deep mantle structure is still not very clear. Here we present high-resolution tomography of 3-D P-wave azimuthal anisotropy down to 400 km depth of the Tonga subduction zone derived from arrival-time data of local earthquakes recorded at seafloor and land seismometers. The subducting Tong slab is imaged as high-velocity anomalies at depths of 100-400 km, whereas large-scale low-velocity anomalies down to 400 km depth are revealed in the mantle wedge beneath the backarc basin and volcanic arc. Trenchparallel anisotropy beneath the Lau Basin extends southwards to ∼140 km depth at ∼20.5 • S, representing the extent of both southward flow of the Samoan plume and toroidal flow by the slab rollback. At depths of 140-400 km, the Lau Basin and Fiji Plateau mainly exhibit plate-parallel fast-velocity directions (FVDs) north of ∼20.5 • S, indicating strong corner flow in the mantle wedge driven by the slab subduction and dehydration. The Tonga slab exhibits trench-parallel FVDs at depths of <200 km, reflecting fossil fabric formed during the plate spreading stage, whereas, at greater depths, the slab mainly exhibits trenchnormal FVDs, which may reflect complicated deformations within the slab. These results suggest that the Samoan plume has a significant impact on the Tonga-Lau-Fiji region, leading to variations in the scale and depth extent of mantle flows.