Challenges in ovarian stimulation.

Abstract : In 2016, ovarian stimulation faces two main challenges: how to obtain good quality oocytes while not endangering the patients treated, but also limited by maternal age and poor ovarian responders (POR). The first IVF birth, Louise Brown, was obtained from a natural cycle. With the introduction, in the 1980s of gonadotropin releasing hormone agonists (GnRHa) and in the 2000s of GnRH antagonists (GnRHant), stimulation became plurifollicular (and source of consequences). Today, only about 50% of the transferred blastocysts after IVF lead to a pregnancy. The purpose of this review was to describe the current challenges and limits of ovarian stimulation.
Complete list of metadatas

https://hal.univ-brest.fr/hal-02043015
Contributor : Ghislaine Calvez <>
Submitted on : Wednesday, February 20, 2019 - 4:54:12 PM
Last modification on : Thursday, February 21, 2019 - 1:33:18 AM

Identifiers

  • HAL Id : hal-02043015, version 1
  • PUBMED : 26930391

Citation

Philippe Merviel, Marie Le Martelot, Sylvie Roche, Caroline Lelièvre, Michel Ménard, et al.. Challenges in ovarian stimulation.. Minerva Ginecologica, Edizione Minerva Medica, 2016, 68 (6), pp.625-41. ⟨hal-02043015⟩

Share

Metrics

Record views

55