HAL will be down for maintenance from Friday, June 10 at 4pm through Monday, June 13 at 9am. More information
Skip to Main content Skip to Navigation
Journal articles

Psychological distress over time in early rheumatoid arthritis: results from a longitudinal study in an early arthritis cohort.

Résumé : Objective. RA is a chronic disease with frequent psychological co-morbidities, of which depression and anxiety are two common manifestations. We aimed to identify predictive factors of psychological distress in a large prospective cohort of very early RA patients. Methods. ESPOIR (Etude et Suivi des Polyarthrites Indifférenciées Récentes) is a multicentre, longitudinal and prospective cohort study of patients with early arthritis (<6 months disease duration). The study sample comprised 641 patients with very early RA according to the 2010 ACR/European League Against Rheumatism RA criteria from the ESPOIR cohort. Psychological distress was assessed over 3 years by the five-item Mental Health Inventory questionnaire at various time points (baseline, 6, 12, 18, 24 and 36 months). Logistic regression with a generalized estimating equation model was used to analyse the association of disease variables and risk of psychological distress. Results. At baseline, 46.9% of RA patients were screened as positive for psychological distress. Over 3 years, psychological distress decreased significantly, with a prevalence of 25.8% at 36 months. The HAQ Disability Index (HAQ-DI) score was the most important factor predicting psychological distress over 3 years [odds ratio 2.10 (95% CI 1.41, 3.14)–3.59 (2.29, 5.63)]. Baseline biological and radiological variables and treatment regimens were not associated with distress. Conclusion. Psychological distress in very early RA is frequent and the HAQ-DI score is a predictor of depression and anxiety in these patients. A psychological evaluation in patients with early RA is important for further individual psychiatric diagnosis and management.
Complete list of metadata

https://hal.univ-brest.fr/hal-01558388
Contributor : Ghislaine Calvez Connect in order to contact the contributor
Submitted on : Friday, July 7, 2017 - 3:35:36 PM
Last modification on : Tuesday, May 17, 2022 - 2:20:02 PM

Links full text

Identifiers

Citation

Ludovic Bacconnier, Nathalie Rincheval, René-Marc Flipo, Philippe Goupille, Jean-Pierre Daures, et al.. Psychological distress over time in early rheumatoid arthritis: results from a longitudinal study in an early arthritis cohort.. Rheumatology, Oxford University Press (OUP), 2015, 54 (3), pp.520-7. ⟨10.1093/rheumatology/keu371⟩. ⟨hal-01558388⟩

Share

Metrics

Record views

135