Investigation of Zr( iv ) and 89 Zr( iv ) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging - Université de Bretagne Occidentale
Journal Articles Chemical Communications Year : 2013

Investigation of Zr( iv ) and 89 Zr( iv ) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging

Abstract

Single crystal X-ray diffraction shows that Zr(IV) forms an octa-coordinated complex with 4 bidentate hydroxamates whose solution structures were investigated by utilizing density functional theory at the level of B3LYP/DGDZVP. Stability constants obtained by potentiometry were in accordance with the tendency observed when radiolabeling with 89Zr.

Dates and versions

hal-01555852 , version 1 (04-07-2017)

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François Guérard, Yong-Sok Lee, Raphaël Tripier, Lawrence P. Szajek, Jeffrey R. Deschamps, et al.. Investigation of Zr( iv ) and 89 Zr( iv ) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging. Chemical Communications, 2013, 49 (10), pp.1002 - 1004. ⟨10.1039/C2CC37549D⟩. ⟨hal-01555852⟩
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