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Patents Year : 2015

Novel branched amphiphilic lipids

Nouveaux lipides amphiphiles ramifiés

Abstract

The present invention relates to novel branched amphiphilic lipids. In particular, the present invention relates to novel branched amphiphilic lipids of general formula (II). The present invention also provides a method for synthesis of said compounds of formula (II) from unsaturated amphiphilic compounds of general formula (I). The invention also relates to the use of compounds of general formula (II) and lipoplexes obtained by formulating the compounds of general formula (II) for applications, including transfection, in which improved melting properties are sought.
The invention relates to novel branched amphiphilic lipids. The invention specifically relates to novel branched amphiphilic lipids of general formula (II). The invention also relates to a method of synthesis for said compounds of formula (II), from unsaturated amphiphilic compounds of general formula (I). The invention further relates to the use of the compounds of general formula (II) and lipoplexes obtained by formulation of the compounds of general formula (II) for applications, particularly transfection, in which improved fusion properties are desired.
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Dates and versions

hal-01532123 , version 1 (02-06-2017)

Identifiers

  • HAL Id : hal-01532123 , version 1

Cite

Paul-Alain Jaffres, Hélène Couthon, Damien Afonso, Tristan Montier, Tony Le Gall. Novel branched amphiphilic lipids. France, Patent n° : WO2017051129 A1. 2015. ⟨hal-01532123⟩
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