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Novel branched amphiphilic lipids

Abstract : The present invention relates to novel branched amphiphilic lipids. In particular, the present invention relates to novel branched amphiphilic lipids of general formula (II). The present invention also provides a method for synthesis of said compounds of formula (II) from unsaturated amphiphilic compounds of general formula (I). The invention also relates to the use of compounds of general formula (II) and lipoplexes obtained by formulating the compounds of general formula (II) for applications, including transfection, in which improved melting properties are sought.
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https://hal.univ-brest.fr/hal-01532123
Contributor : Nicolas Renard <>
Submitted on : Friday, June 2, 2017 - 2:47:36 PM
Last modification on : Thursday, November 29, 2018 - 4:09:13 PM

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  • HAL Id : hal-01532123, version 1

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Paul-Alain Jaffres, Hélène Couthon, Damien Afonso, Tristan Montier, Tony Le Gall. Novel branched amphiphilic lipids. France, Patent n° : WO2017051129 A1. 2015. ⟨hal-01532123⟩

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