Triggering bilayer to inverted-hexagonal nanostructure formation by thiol–ene click chemistry on cationic lipids: consequences on gene transfection - Université de Bretagne Occidentale Access content directly
Journal Articles Soft Matter Year : 2016

Triggering bilayer to inverted-hexagonal nanostructure formation by thiol–ene click chemistry on cationic lipids: consequences on gene transfection

Abstract

The ramification of cationic amphiphiles on their unsaturated lipid chainsisreadilyachievedbyusingthethiol–eneclickreactiontriggering the formation of an inverted hexagonal phase (HII). The new ramified cationic lipids exhibit different bio-activities (transfection, toxicity) including higher transfection efficacies on 16HBE 14o-cell lines.
No file

Dates and versions

hal-01517791 , version 1 (03-05-2017)

Identifiers

Cite

Damien Afonso, Tony Le Gall, Hélène Couthon, Axelle Grélard, Shipra Prakash, et al.. Triggering bilayer to inverted-hexagonal nanostructure formation by thiol–ene click chemistry on cationic lipids: consequences on gene transfection. Soft Matter, 2016, 12 (20), pp.4516 - 4520. ⟨10.1039/c6sm00609d⟩. ⟨hal-01517791⟩
112 View
0 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More