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American consensus recommendations for gastric scintigraphy: curve fitting with only a few points remains an easy and accurate method to obtain reliable and reproducible gastric emptying estimates.

Abstract : BACKGROUND: In 2008, American consensus recommendations for performing gastric emptying (GE) scintigraphy were published. It was recommended that data are acquired only at 0, 1, 2, and 4 h and that the results are expressed as percentages of meal retention. Until now, it was established that the GE time-activity curves should have many points (every 10, 15, or 20 min) to reflect the GE process accurately and to be optimally adjusted by a mathematical model. In this study, we have evaluated the curve fitting using only a few points as proposed by the consensus protocol. MATERIALS AND METHODS: GE scintigraphy tests of 224 patients were retrospectively analyzed. Two curve fittings were done for each patient, either using data acquired every 20 min or using data acquired every hour. A comparison of these two methods was made based on the values of the computed GE parameters. RESULTS: We observed strong correlations between the two methods (r=0.81-0.99, P<0.05). Using the Bland-Altman analysis, more than 95% of the differences were included in the mean difference 95% confidence interval. The mean differences were weak with a relatively small SD and Cohen's k coefficients ranging from 0.84 to 0.93, indicating an excellent agreement between the two methods. CONCLUSION: Our results showed the feasibility and accuracy of curve fitting using only a few points. The curve fitting is easy to perform and allows the computation of reliable and reproducible parameters that reflect the whole GE process.
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https://hal.univ-brest.fr/hal-00931168
Contributor : Ghislaine Calvez Connect in order to contact the contributor
Submitted on : Wednesday, January 15, 2014 - 8:53:11 AM
Last modification on : Thursday, March 31, 2022 - 11:00:02 AM

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Pierre-Yves Le Roux, Francis Bouchet, Solène Querellou, Laurent Vervueren, Franck Lacoeuille, et al.. American consensus recommendations for gastric scintigraphy: curve fitting with only a few points remains an easy and accurate method to obtain reliable and reproducible gastric emptying estimates.. Nuclear Medicine Communications, Lippincott, Williams & Wilkins, 2011, 32 (1), pp.30-6. ⟨10.1097/MNM.0b013e3283404270⟩. ⟨hal-00931168⟩

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