Diagnostic value of a negative single complete compression ultrasound of the lower limbs to exclude the diagnosis of deep venous thrombosis in pregnant or postpartum women: a retrospective hospital-based study.

Grégoire Le Gal; Anne-Marije Prins; Marc Righini; Caroline Bohec; Karine Lacut; Pierre Germain; Jean-Claude Vergos; Raymond Kaczmarek; Bruno Guias; Michel Collet; Luc Bressollette; Emmanuel Oger; Dominique Mottier

doi:10.1016/j.thromres.2005.12.004

Diagnostic value of a negative single complete compression ultrasound of the lower limbs to exclude the diagnosis of deep venous thrombosis in pregnant or postpartum women: a retrospective hospital-based study.

Grégoire Le Gal ^{1, 2, *} Anne-Marije Prins ³ Marc Righini ⁴ Caroline Bohec Karine Lacut ^{1, 2} Pierre Germain ⁵ Jean-Claude Vergos ⁶ Raymond Kaczmarek ⁷ Bruno Guias ³ Michel Collet ^{1, 8} Luc Bressollette ⁹ Emmanuel Oger ² Dominique Mottier ^{1, 2}

* Auteur correspondant

1 GETBO - Groupe d'Etude de la Thrombose de Bretagne Occidentale

2 CIC - Brest - Centre d'Investigation Clinique

3 DMIP - Brest - Département de Médecine Interne et Pneumologie [Brest]

4 MR - Service d'angiologie et d'hémostase

5 CHIC - Gynécologie - Service de Gynécologie

6 CHIC - Radiologie - Service de Radiologie

7 CHPM - Gynécologie - Service de Gynécologie

8 BREST - Gynéco-Obs - Service de Gynécologie-Obstétrique

9 CHRU Brest - Centre Hospitalier Régional Universitaire de Brest

Abstract : OBJECTIVE: We aimed at determining whether a negative single complete compression ultrasonography (CUS) of the lower limbs veins is a safe and accurate diagnostic method to rule out the diagnosis of deep venous thrombosis in pregnant and early postpartum women. DESIGN: Hospital-based retrospective study. SETTING: The gynaecology and vascular ultrasound units of three general hospitals in western France. PATIENTS: We identified from the hospitals databases all pregnant or up to three months postpartum women who underwent CUS for a suspicion of deep venous thrombosis between January 2002 and December 2004. METHODS: Questionnaires were sent to all women with a negative CUS. Their medical records were also checked. MAIN OUTCOME MEASURES: We assessed the three-month thromboembolic risk and its 95% percent confidence interval in women left untreated on the basis of a negative single complete CUS of the lower limbs. RESULTS: During the study period, 162 pregnant or postpartum women underwent CUS for a suspicion of deep venous thrombosis. It was positive in 44 (27%). The 118 women who had a negative CUS were sent the questionnaire. Information about the three-month follow-up was found for 107 patients (91%). None of them experienced a thromboembolic event during follow-up: 0.0% (95% CI: 0.0-3.6). CONCLUSIONS: Single complete CUS of lower limbs veins appears to be a safe method to rule out the diagnosis of deep venous thrombosis in pregnant or early postpartum women. This has to be confirmed by a prospective management study with a formal follow-up.

Type de document :

Article dans une revue

Thrombosis Research, Elsevier, 2006, 118 (6), pp.691-7. 〈10.1016/j.thromres.2005.12.004〉

Domaine :

Sciences du Vivant [q-bio] / Médecine humaine et pathologie

Liste complète des métadonnées

http://hal.univ-brest.fr/hal-00688998
Contributeur : Ghislaine Calvez <>
Soumis le : jeudi 19 avril 2012 - 10:30:21
Dernière modification le : lundi 28 mai 2018 - 18:06:02

Diagnostic value of a negative single complete compression ultrasound of the lower limbs to exclude the diagnosis of deep venous thrombosis in pregnant or postpartum women: a retrospective hospital-based study.

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Diagnostic value of a negative single complete compression ultrasound of the lower limbs to exclude the diagnosis of deep venous thrombosis in pregnant or postpartum women: a retrospective hospital-based study.

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