Diagnostic value of a negative single complete compression ultrasound of the lower limbs to exclude the diagnosis of deep venous thrombosis in pregnant or postpartum women: a retrospective hospital-based study.

Grégoire Le Gal 1, 2, * Anne-Marije Prins 3 Marc Righini 4 Caroline Bohec Karine Lacut 1, 2 Pierre Germain 5 Jean-Claude Vergos 6 Raymond Kaczmarek 7 Bruno Guias 3 Michel Collet 1, 8 Luc Bressollette 9 Emmanuel Oger 2 Dominique Mottier 1, 2
* Auteur correspondant
1 GETBO - Groupe d'Etude de la Thrombose de Bretagne Occidentale
2 CIC - Brest - Centre d'Investigation Clinique
3 DMIP - Brest - Département de Médecine Interne et Pneumologie [Brest]
4 MR - Service d'angiologie et d'hémostase
5 CHIC - Gynécologie - Service de Gynécologie
6 CHIC - Radiologie - Service de Radiologie
7 CHPM - Gynécologie - Service de Gynécologie
8 BREST - Gynéco-Obs - Service de Gynécologie-Obstétrique
9 CHRU Brest - Centre Hospitalier Régional Universitaire de Brest
Abstract : OBJECTIVE: We aimed at determining whether a negative single complete compression ultrasonography (CUS) of the lower limbs veins is a safe and accurate diagnostic method to rule out the diagnosis of deep venous thrombosis in pregnant and early postpartum women. DESIGN: Hospital-based retrospective study. SETTING: The gynaecology and vascular ultrasound units of three general hospitals in western France. PATIENTS: We identified from the hospitals databases all pregnant or up to three months postpartum women who underwent CUS for a suspicion of deep venous thrombosis between January 2002 and December 2004. METHODS: Questionnaires were sent to all women with a negative CUS. Their medical records were also checked. MAIN OUTCOME MEASURES: We assessed the three-month thromboembolic risk and its 95% percent confidence interval in women left untreated on the basis of a negative single complete CUS of the lower limbs. RESULTS: During the study period, 162 pregnant or postpartum women underwent CUS for a suspicion of deep venous thrombosis. It was positive in 44 (27%). The 118 women who had a negative CUS were sent the questionnaire. Information about the three-month follow-up was found for 107 patients (91%). None of them experienced a thromboembolic event during follow-up: 0.0% (95% CI: 0.0-3.6). CONCLUSIONS: Single complete CUS of lower limbs veins appears to be a safe method to rule out the diagnosis of deep venous thrombosis in pregnant or early postpartum women. This has to be confirmed by a prospective management study with a formal follow-up.
Type de document :
Article dans une revue
Thrombosis Research, Elsevier, 2006, 118 (6), pp.691-7. 〈10.1016/j.thromres.2005.12.004〉
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https://hal.univ-brest.fr/hal-00688998
Contributeur : Ghislaine Calvez <>
Soumis le : jeudi 19 avril 2012 - 10:30:21
Dernière modification le : jeudi 29 novembre 2018 - 16:09:29

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GETBO | UNIV-BREST | IBSAM

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Grégoire Le Gal, Anne-Marije Prins, Marc Righini, Caroline Bohec, Karine Lacut, et al.. Diagnostic value of a negative single complete compression ultrasound of the lower limbs to exclude the diagnosis of deep venous thrombosis in pregnant or postpartum women: a retrospective hospital-based study.. Thrombosis Research, Elsevier, 2006, 118 (6), pp.691-7. 〈10.1016/j.thromres.2005.12.004〉. 〈hal-00688998〉

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