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, Annexe 5 : Quantification du malondihaldéhyde (MDA)

, * La phase mobile utilisée est constituée d'un mélange de 65% de tampon phosphate KH 2 PO 4 (10 mM) et de 35% de méthanol. Le pH est ajusté à 5,8 avec de la potasse (KOH 1 M) puis la solution est filtrée (0,45 µm) et dégazée avant d'être utilisée

*. Le-complexe and T. Mda, de couleur rose) est séparé par HPLC (colonne Hypersil ODS ; 4,6 mm x 150 mm, particules greffées de 5 µm) et est détecté au spectrophotomètre UV à 532nm

M. Chromatogramme-type-représentant-le-complexe,

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, At each step, the water inflow was closed and the decrease in P WO2 then recorded for 30 min. The MO 2 was calculated always over the first 10

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. Mckenzie, This value was still higher than the critical partial oxygen pressure, which did not exceed 4 kPa in eels in this range of temperatures (Cruz-Neto and Steffensen, 1997.

B. Sébert, Temperature sensitivity was evaluated by calculating Q 10 following the equation, vol.10, 1981.

, or polynomial) were used according to the best correlation obtained. The significance of the correlation coefficient (R) was validated by the Pearson test. The Q 10 values and HR/MO 2 relationship were expressed by the mean ± SD. Statistical significance was evaluated with paired Student

, In the range of experimental temperatures (5 to 25°C), MO 2 and HR plotted against temperature revealed exponential relationships (y = ae bx ) and both regressions were significant

, For the same range of temperatures, HR also showed increased values from around 10 to 75 BPM (figure 1a). The OP decreased significantly

, The Q 10 values for MO 2 , HR and OP were calculated over temperature changes between 5-15°C, Figure 1: Effect of temperature on: a-heart rate

, N = 9

, This barrier is illustrated in figure 4a (the horizontal dashed line) and in figure 5 (the vertical dashed line). This HR barrier (around 8 MPa) could correspond to the pressure threshold that matches the pressure at which the eel begins to have seizures, 20°C and during the pressure protocol at 10.1 MPa, the related HR were different (respectively 60 and 46 BPM), 1985.

, The stagnation of HR translates to an inhibitory chronotrope effect, which could be explained through vagal activation or through the release of catecholamines (mainly norepinephrine and epinephrine) from the chromaffin tissue and adrenergic nerve endings

, Indeed, exposure to 10.1 MPa for one hour does not modify catecholamine content in the heart

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