Transformation d’un mélanocytome méningé en mélanome : étude clinique, histopathologique et cytogénétique - Université de Bretagne Occidentale Access content directly
Journal Articles Annales de Pathologie Year : 2019

[Meningeal melanoma arising from a preexisting meningeal melanocytoma: A clinical, pathological and cytogenetic study about one case].

Transformation d’un mélanocytome méningé en mélanome : étude clinique, histopathologique et cytogénétique

Abstract

Meningeal melanocytic tumors are rare. We report an exceptional case of transformation of a meningeal melanocytoma in a malignant melanoma. The course of the disease extents from 61-years to 85-years and ends with the death of the patient. Besides histopathological and immunohistochemical data, we also report the array CGH study of the melanocytoma and melanoma components suggesting the malignant transformation from whole chromosome gains in the melanocytoma to additional segmental aberrations in the malignant melanoma. Beyond the rarity of this tumor subtype, this case report highlights the potential interest of molecular analyses for diagnostic and prognostic purposes in the field of meningeal melanocytic tumors.
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hal-02262437 , version 1 (20-07-2022)

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Amélie Bourhis, Isabelle Quintin-Roué, Sylvia Redon, Marianne Bourhis, Elsa Magro, et al.. Transformation d’un mélanocytome méningé en mélanome : étude clinique, histopathologique et cytogénétique. Annales de Pathologie, 2019, ⟨10.1016/j.annpat.2019.01.010⟩. ⟨hal-02262437⟩
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