Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial

William Busse 1 Peter Barker Stephanie Sproule Richard Olsson Ubaldo Martin Mitchell Goldman Anahí Yañez Marcelo Fernández Alberto Tolcachier Juan Belloni Jorge Taborda Maria de Salvo Jorge Maspero 2 Carlos Victorio Miguel Chirino Navarta Monica Grilli Pablo Rodríguez María Otaola Víctor Cambursano Patricia Malamud Ana Stok German Arce Osiris Roza Fernando Scherbovsky Pedro Elias Maria Saez Peter Peters 3 John Upham Peter Gibson 4 Francis Thien Jo Douglass Paul Thomas 5 Philip Bardin Dimitar Sajkov Mark Hew David Langton Andreia Pez Carlos Fritscher Jorge Hetzel Waldo Mattos Rafael Stelmach Martti Antila Ana Fernandes 6 Hristo Metev Yavor Ivanov Aneliya Bogdanova Ana Markova Marinka Peneva Rumyana Veselinova Tatyana Petkova Vanushka Petrova Elena Shopova Yuliya Ivanov Rumyana Yotsova Ginka Kirkova Galina Petrova Svetoslav Dachev Kostadinka Sotirova Mariyana Stoyanova Oleg Yakov Vanya Ilieva-Fartunova Catherine Lemiere Michel Laviolette William Yang J Mark Fitzgerald Bonavuth Pek William Killorn Claude Poirier 7 Guy Chouinard Lyle Melenka Richard Leigh 8 Parameswaran Nair Delbert Dorscheid Juan Pavie Andres Rosenblut Claudia Cartagena Carlos Quilodran Silvia Muñoz Ivana Malkusova Jo Veverka Stanislav Holub Jaroslav Mares Radovan Kozel Daniela Kopecka Vladimir Zindr Pavel Cerva Pascal Chanez 9 Arnaud Bourdin 10 Gilles Devouassoux 11 Camille Taillé 12 Fréderic de Blay 13 François Goupil 14 Christophe Leroyer 15, 16 Delphine Gourcerol Toufik Didi 17 Alain Didi Gilles Garcia 18 Philip Bonniaud Riazate Rossanaly Vasram Marek Lommatzsch Ulf Harnest Anneliese Linnhoff Claus Keller Gerhard Hoheisel Karin Förster Thomas Thomas Isabelle Schenkenberger Jo Kirschner Tibor Schmoller Stefan Zielen 19 Marc Kornmann Ekkehard Beck Lutz Volgmann Rolf Dichmann Axel Overlack Jörg Winkler Petra Mikloweit Sabine Ballenberger Mathias Rolke Stephanie Korn Helmut Pabel Martin Martin Jan Feimer Klaus Rabe 20 Regina Deckelmann Tobias Welte 21 Hiroyuki Ohbayashi Soichiro Hozawa Terufumi Shimoda Makoto Yoshida Toshikazu Nagakura Tadashi Kamei Yasuyuki Sano Shinichiro Kagami Hisaho Takahashi Michiko Haida Goro Kimura Hiroyuki Nakamura 22 Yasuo To Masaharu Shinkai Tadasuke Shimokawaji Makoto Kudo Noriharu Shijyubo Takao To Motokazu Kato Akihiko Tanaka Yasuhiro Gon Norihisa Sasaki Tetsuro Ohdaira Chiharu Omori Toshiki Takahashi Satomi Takeuchi Kiyotaka Nakajima Hironi Makita Masahiro Kaneko Kenjiro Furuta Masami Taniguchi Yoshito Inobe Hiroshi Miki Yoichi Nakamura Naoki Miyazawa Shuichi Yano Masayuki Iijima Tsuyoshi Yamato Javier Diaz Alberto Matsuno Efrain Felix Alfredo Guerreros Alejandro Daly Fernando Rodriguez Chariarse Danilo Salazar Socorro Castro William Chavez Rolando Estrella Teresita Aquino Tito Atienza Ronnie Samoro Marie Grace Dawn Isidro Piotr Kuna 23 Adam Antczak Michał Bednarek Danuta Mądra-Rogacka Teresa Hofman Marek Jutel 24 Ewa Pisarczyk-Bogacka Agata Kot Robert Mróz Małgorzata Czupryńska-Borkowska Małgorzata Żurowska-Gębala Andrzej Dyczek Grażyna Jasieniak-Pinis Piotr Wojnowski Ewa Trębas-Pietraś Małgorzata Dobryniewska Marc Stobiecki Marzenna Tarnowska-Matusiak Alina Magner Andrzej Kolczyński Zbigniew Bartuzi Bernadetta Majorek-Olechowska Paweł Śliwiński Violetta Balicka Elżbieta Hajoł Jacek Stachera Marta Rachel Marek Michnar Jarosław Tałałaj Ewa Springer Piotr Napora Renata Bijata-Bronisz Anna Świderska Grzegorz Mincewicz Zbigniew Sankowski Tomasz To Artur Kwaśniewski Jo Jerzyńska Jerzy Cygler Ryszard Olesiejuk Iwona von Steiner Wojciech Machowiak Krzysztof Filipek Piotr Piskorz Ewa Uhryn Marita Nittner-Marszalska Elżbieta Rybicka-Liszewska Anna Bodzenta-Łukaszyk Marta Chełmińska Izabella Krupa-Borek Wojciech Skucha Anna Płoszczuk Traian Mihaescu Ioan Dorin Petrui Angelica Savu Ghiulten Apti Claudia To Ana Trailescu Sergei Sokurenko Vasiliy Trofimov Igor Leshchenko Natalia Shaporova Inna Ilyashevich Irina Stitsenko Alexander Vizel Yulia Ilkovich Dmitrii Tikhanov Svetlana Gon Andrey Ezhov Galina Ignatova Nadezhda Izmozherova Nadezhda Berdnikova Ludmila Goryachkina Veronika Popova Laura Bolieva Andrey Rebrov Vladimir Nosov Olga Magnitskaya Sergey Nedogoda Vladimir Abrosimov Artem Molotkov Galina Reshedko Mikhail Smirnov 25 Marina Osipenko Elena Pavlysh Svetlana Myasoedova Liudmila Lenskaya Valery Chistyakov Elena Vishneva Liliya Uon Anna Zateyschikova Svetlana Laleko Tatiana Pak Axel Bruning Visvakuren Naidoo Jeevren Reddy Richard van Zyl Smit Hae-Sim Park Jo Cho Sang-Heon Cho Sang Haak Lee Byung Jae Lee Ju Sang Kim You Sook Cho Choon-Sik Park Mi-Kyeong Kim Young-Il Koh Jo Kim Sook Young Lee Sang Pyo Lee Jung Won Park Kwang Ha Yoo Hyoungkyu Yoo Jaechun Lee Gyu-Young Hur Soo Keol Lee Heekyoo Kim David Ramos Barbón Elena Laffond Yges Eva Martínez Moragón Miguel Arias Guillen Alberto Saura Vinuesa Fernando To Jo Velasco Garrido Borja García-Cosio Piqueras Luis Pérez de Llano Luis Valero Santiago Myriam Calle Rubio Leif Bjermer Bo Lundbäck Bilun Gemicioglu Sevim Bavbek 26 Dane Ediger Munevver Erdinc Ismail Hanta Sibel Nayci Sibel Arinc Liudmyla Iashyna Yuriy Mostovoy Mykola Ostrovskyy Lesia Kuryk Ivan Lemko Tetyana Ospanova Liubov Moskalenko Oleksii Korzh Viktor Blazhko Olena Krakhmalova Liliia Romaniuk Yevgeniya Dytyatkovs'Ka Oleh Yakov Volodymyr Gavrysyuk Hassan Burhan Dinesh Saralaya Stephen Scott 27 Alyn Morice Ewa Jackson-Voyzey Thida Win Shuab Nasser Richard Harrison 28 Rekha Chaudhuri Monica Nordstrom Pradip De Matthew Masoli Adel Mansur Anthony Gunstone Robert Niven Timothy Harrison Suresh Babu Subodh Bhuchar Shahrukh Kureishy John Zwetchkenbaum Lawrence Kaplan Eugene Bleecker 29 Santiago Reyes 30 Faisal Fakih Marvin Heuer Ryan Klein Marc Marcus Iftikhar Hussain 31 Tonny To Hengameh Raissy Sady Alpizar Hector Rodriguez 32 Gerald Gleich Tracy Bridges Jo Pouzar Gary Steven Jo Matz Shana Krstevska Dama Ziworitin Adolfo Kaplan James Sublett James De Amy Darter John Agaiby John Hagan Enrique Davis Dareen Siri Charlene Mcevoy Chrisette Dharma Najmuddin Karimjee Steven Steven Manuel Frade Amy Silverthorn Jo Kline Francis Averill Jo Ruiz Emory Robinette Zeeshan Shaikh Carlos Aguilar William Nish German Alvarez Ismail Ismail Purvi Parikh Mila Leong Dennis De Francis Garcia 33 Alan Goldsobel Antonio Blanco Edward Campbell Guido Perez Geoffrey Chupp Toby To Vandely Perez Sally Wenzel Kartik Shenoy Rohit Katial David Bernstein Neil Parikh William Sims Gary Ferguson David Pham Anu George Richard Beasley Gilberto Pérez 34 Robert Garver Miriam Garcia Stephen Wong Weily Soong Richard Guillot Golda Hudes Ahmed Arif Jo Binker Manuel Villareal Ulrike Ziegner Jo Ojile Sanjeev Goswami Carlos Piniella Ilia Segal Heidi Zafra Mitchell Lee Martha Tarpay John Panuto Rajan Merchant Peter Springsteen Timothy Scialla Paul Shapero Karen Allen Mark Moss Humberto Cruz Jeffrey Rumbyrt Bo Boyd Robert Nathan Jo Bernstein Jo Jacobs Elliot Ginchansky John Johnston Barbara Baxter John Thomas Stephen Apaliski Clinton Corder David Fuentes Jo Diaz Chau Ngo Lan Le
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https://hal.univ-brest.fr/hal-02052347
Contributor : Ghislaine Calvez <>
Submitted on : Thursday, February 28, 2019 - 2:08:24 PM
Last modification on : Thursday, July 11, 2019 - 9:15:01 AM

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  • HAL Id : hal-02052347, version 1

Citation

William Busse, Peter Barker, Stephanie Sproule, Richard Olsson, Ubaldo Martin, et al.. Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial. Lancet Respiratory medicine, Elsevier, 2019, 7 (1), pp.46-59. ⟨hal-02052347⟩

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