HAL will be down for maintenance from Friday, June 10 at 4pm through Monday, June 13 at 9am. More information
Skip to Main content Skip to Navigation
Journal articles

B cells in Sjögren’s syndrome: from pathophysiology to therapeutic target

Abstract : Biological abnormalities associated with B lymphocytes are a hallmark of patients with primary Sjögren's syndrome. Those patients present abnormal distribution of B lymphocytes in peripheral blood and B cells in exocrine glands. B cells produce auto-antibodies, cytokines and present antigens but can also suppressive functions. In this review, we will summarize current knowledge on B cells in primary Sjögren's syndrome patients, demonstrate their critical role in the immunopathology of the disease and describe the past and current trials targeting B cells.
Document type :
Journal articles
Complete list of metadata

Contributor : Geneviève Michel Connect in order to contact the contributor
Submitted on : Monday, February 25, 2019 - 2:30:31 PM
Last modification on : Tuesday, May 17, 2022 - 2:20:02 PM




Julie Mielle, Alice Tison, Divi Cornec, Laëtitia Le Pottier, Claire Daien, et al.. B cells in Sjögren’s syndrome: from pathophysiology to therapeutic target. Rheumatology, Oxford University Press (OUP), 2019, ⟨10.1093/rheumatology/key332⟩. ⟨hal-02048234⟩



Record views