Skip to Main content Skip to Navigation
Journal articles

Phosphonolipids as non-viral vectors for gene therapy

Abstract : Several phosphonates with two fatty chains and different polar heads were synthesized and evaluated for their potential to transfer DNA into epithelial (COS-7) and hematopoietic (K562) cell lines, and compared to commercially available references. In both cases, ammonium-phosphonates were particularly efficient.
Document type :
Journal articles
Complete list of metadatas

https://hal.univ-brest.fr/hal-01770726
Contributor : Nicolas Renard <>
Submitted on : Thursday, April 19, 2018 - 10:58:10 AM
Last modification on : Thursday, November 29, 2018 - 4:09:10 PM

Links full text

Identifiers

Collections

Citation

V. Floch, G. Le Bolc'H, C. Gable-Guillaume, Nathalie Le Bris, J.-J. Yaouanc, et al.. Phosphonolipids as non-viral vectors for gene therapy. European Journal of Medicinal Chemistry, Elsevier, 1998, 33, pp.923--934. ⟨10.1016/S0223-5234(99)80017-8⟩. ⟨hal-01770726⟩

Share

Metrics

Record views

124