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Article Dans Une Revue European Journal of Medicinal Chemistry Année : 1998

Phosphonolipids as non-viral vectors for gene therapy

Résumé

Several phosphonates with two fatty chains and different polar heads were synthesized and evaluated for their potential to transfer DNA into epithelial (COS-7) and hematopoietic (K562) cell lines, and compared to commercially available references. In both cases, ammonium-phosphonates were particularly efficient.

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https://hal.univ-brest.fr/hal-01770726

Soumis le : jeudi 19 avril 2018-10:58:10

Dernière modification le : mercredi 17 avril 2024-12:46:17

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hal-01770726 , version 1 (19-04-2018)

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V. Floch, G. Le Bolc'H, C. Gable-Guillaume, Nathalie Le Bris, J.-J. Yaouanc, et al.. Phosphonolipids as non-viral vectors for gene therapy. European Journal of Medicinal Chemistry, 1998, 33, pp.923--934. ⟨10.1016/S0223-5234(99)80017-8⟩. ⟨hal-01770726⟩

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