Fast colorimetric evaluation of optimum conditions for the synthesis of fluorescent molecular probes: Application to neuronal tracers N,N-((dialkyiamino)styryl)-N-alkylpyridinium salts
Abstract
The present communication reports the detection of new phosphorus- containing semilabile ligands for the Heck coupling reaction. We have developed a new screening methodology based on the batochrome properties of the cross-conjugated target molecules to rapidly test a large diversity of metal/ligand complexes for this coupling reaction. © 2005 Wiley-VCH Verlag tGmbH & Co. KGaA.