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Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial.

Résumé : New therapeutic options are needed for patients with psoriasis. Tofacitinib, an oral Janus kinase inhibitor, is being investigated as a treatment for moderate-to-severe chronic plaque psoriasis. In this study, we aimed to compare two tofacitinib doses with high-dose etanercept or placebo in this patient population.
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https://hal.univ-brest.fr/hal-01558410
Contributor : Ghislaine Calvez <>
Submitted on : Friday, July 7, 2017 - 4:05:16 PM
Last modification on : Wednesday, August 19, 2020 - 11:17:26 AM

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  • HAL Id : hal-01558410, version 1
  • PUBMED : 26051365

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Hervé Bachelez, Peter C M van de Kerkhof, Robert Strohal, Alexey Kubanov, Fernando Valenzuela, et al.. Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial.. Lancet, Elsevier, 2015, 386 (9993), pp.552-61. ⟨hal-01558410⟩

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