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SPP1 rs9138 variant contributes to the severity of radiological damage in anti-citrullinated protein autoantibody-negative rheumatoid arthritis.

Résumé : We recently reported an association of the SPP1 rs9138 and rs11439060 functional variants with the risk of rheumatoid arthritis (RA), the association being greater in anti-citrullinated protein autoantibody (ACPA)-negative patients. We hypothesised that SPP1 may contribute to the severity of joint destruction in RA, specifically in the ACPA-negative population.
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https://hal.univ-brest.fr/hal-01558243
Contributor : Ghislaine Calvez Connect in order to contact the contributor
Submitted on : Friday, July 7, 2017 - 1:03:17 PM
Last modification on : Tuesday, October 19, 2021 - 11:54:35 PM

Identifiers

  • HAL Id : hal-01558243, version 1
  • PUBMED : 24936586

Citation

Pierre-Antoine Juge, Hanna W van Steenbergen, Arnaud Constantin, Gabriel J Tobon, Thierry Schaeverbeke, et al.. SPP1 rs9138 variant contributes to the severity of radiological damage in anti-citrullinated protein autoantibody-negative rheumatoid arthritis.. Annals of the Rheumatic Diseases, BMJ Publishing Group, 2014, 73 (10), pp.1840-3. ⟨hal-01558243⟩

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