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ESPOIR and the French database management: what have we learned from the first years of follow-up?

Abstract : ESPOIR (Etude et Suivi des POlyarthrites Indifférenciées Récentes) is a multicentre national cohort sponsored by the French Society for Rheumatology. The patients had early arthritis (<6-month disease duration), had a certain/probable clinical diagnosis of RA or undifferentiated arthritis potentially becoming RA and were DMARDs or glucocorticoids naïve. ESPOIR is a cohort of early arthritis, highly enriched for rheumatoid arthritis (RA) patients, since in patients followed for 5 years more than 90% met ACR/EULAR criteria for RA. A total of 813 patients were enrolled between December 2002 and March 2005 in 14 academic regional centres with the participation of a network of private rheumatologists. Today, 104 clinical research projects have been selected by the scientific committee of the cohort. The projects focus on data from the first 5 years of follow-up. Many studies are in progress, and 54 original articles have been published. The research projects cover a wide range of topics, including environmental factors, diagnosis, evolution, and prognosis, evaluation of disease, imaging, genetics, biomarkers, medical economics and therapeutic strategies.
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https://hal.univ-brest.fr/hal-01558242
Contributor : Ghislaine Calvez <>
Submitted on : Friday, July 7, 2017 - 1:00:21 PM
Last modification on : Friday, May 15, 2020 - 12:22:04 PM

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  • HAL Id : hal-01558242, version 1
  • PUBMED : 25365107

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B Combe, Alain Saraux. ESPOIR and the French database management: what have we learned from the first years of follow-up?. Clinical and experimental rheumatology, Clinical and Experimental Rheumatology Sas, 2014, 65 (12), pp.S-153-7. ⟨hal-01558242⟩

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