The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome.

Résumé : Interferon regulatory factor 5 is a transcription factor involved in type I interferon (IFN) secretion. This study was undertaken to investigate whether a 5-bp (CGGGG insertion/deletion) promoter polymorphism is involved in genetic predisposition to primary Sjögren's syndrome (SS) and to assess the functional consequences of this polymorphism.
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Article dans une revue
Arthritis and Rheumatism, Wiley, 2009, 60 (7), pp.1991-7
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http://hal.univ-brest.fr/hal-01558128
Contributeur : Ghislaine Calvez <>
Soumis le : vendredi 7 juillet 2017 - 10:33:52
Dernière modification le : jeudi 12 avril 2018 - 11:08:16

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  • HAL Id : hal-01558128, version 1
  • PUBMED : 19565491

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Corinne Miceli-Richard, Nicolas Gestermann, Marc Ittah, Emmanuelle Comets, Pascale Loiseau, et al.. The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome.. Arthritis and Rheumatism, Wiley, 2009, 60 (7), pp.1991-7. 〈hal-01558128〉

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