Diagnostic criteria for autoimmune neutropenia.

Pierre Youinou 1, 2, 3 Christophe Jamin 2, 1 Laëtitia Le Pottier 2, 1 Yves Renaudineau 2, 3, 1 Sophie Hillion 2, 1 Jacques-Olivier Pers 2, 1
1 LabEX IGO Immunothérapie Grand Ouest
2 EA2216 - Immunologie et Pathologie
3 Laboratoire d'Immunologie et Immunothérapie
Abstract : : Autoimmune neutropenia denotes that the number of circulating polymorphonuclear neutrophils is below 1.5×10(9)/L. This encompasses a wide range of disorders from primary conditions to complications of systemic autoimmune diseases or hematological neoplasms. Antineutrophil autoantibodies are particularly difficult to detect, and their amount does not correlate with the degree of neutropenia. Granulocyte colony-stimulating factor is the first-line therapy, but should be restricted to patients with total absence of neutrophils and/or severe infections.
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Article dans une revue
Autoimmunity Reviews, Elsevier, 2014, 13 (4-5), pp.574-576. 〈10.1016/j.autrev.2014.01.001〉
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Contributeur : Geneviève Michel <>
Soumis le : jeudi 27 mars 2014 - 15:08:37
Dernière modification le : mercredi 29 novembre 2017 - 14:53:44

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Pierre Youinou, Christophe Jamin, Laëtitia Le Pottier, Yves Renaudineau, Sophie Hillion, et al.. Diagnostic criteria for autoimmune neutropenia.. Autoimmunity Reviews, Elsevier, 2014, 13 (4-5), pp.574-576. 〈10.1016/j.autrev.2014.01.001〉. 〈hal-00966888〉

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