Early and long-term results of unprotected left main coronary artery stenosis with paclitaxel-eluting stents: the FRIEND (French multicentre RegIstry for stenting of uNprotecteD LMCA stenosis) registry. - Université de Bretagne Occidentale Access content directly
Journal Articles EuroIntervention Year : 2011

Early and long-term results of unprotected left main coronary artery stenosis with paclitaxel-eluting stents: the FRIEND (French multicentre RegIstry for stenting of uNprotecteD LMCA stenosis) registry.

Hélène Eltchaninoff
  • Function : Author
Thierry Lefèvre
Marc Silvestri
  • Function : Author
Philippe Brunel
  • Function : Author
Jean Fajadet
  • Function : Author
Anouska Moynagh
  • Function : Author
René Koning
  • Function : Author
Alain Dibie
  • Function : Author
Olivier Darremont
  • Function : Author
Jean Marc Lablanche
  • Function : Author
Didier Blanchard
  • Function : Author
Non Renseigné
  • Function : Author

Abstract

AIMS: To evaluate the angiographic and clinical outcome of patients undergoing paclitaxel-eluting stent (PES) implantation for unprotected left main coronary artery (ULMCA) stenosis in a "real-world" multicentre, prospective registry. Percutaneous coronary intervention (PCI) is an increasingly utilised method of revascularisation in patients with ULMCA. METHODS AND RESULTS: A prospective registry including all patients with a significant (>50%) ULMCA stenosis. Of 151 such patients, the target lesion involved the distal bifurcation in 100 patients (66%), which was treated predominantly by a "provisional T-stenting" strategy. In the distal ULMCA disease group, 72% had only one stent implantation while 28% had multiple (either two or three) stents implanted. At a median follow-up of 1,123±80 days, cardiac death occurred in five patients (3.3%) and major adverse cardiac and cerebrovascular events (MACCE) in 32 patients (21.2%). The three-year survival rate was 93.3%. CONCLUSIONS: In the drug-eluting stent era, paclitaxel-eluting stent implantation of ULMCA stenosis provided excellent immediate and long-term results in this selected population, suggesting that this approach may be considered as a safe and effective alternative to CABG for selected patients with ULMCA who are treated in experienced institutions performing large numbers of PCI procedures.
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Dates and versions

hal-00812270 , version 1 (11-04-2013)

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Didier Carrié, Hélène Eltchaninoff, Thierry Lefèvre, Marc Silvestri, Philippe Brunel, et al.. Early and long-term results of unprotected left main coronary artery stenosis with paclitaxel-eluting stents: the FRIEND (French multicentre RegIstry for stenting of uNprotecteD LMCA stenosis) registry.. EuroIntervention , 2011, 7 (6), pp.680-8. ⟨10.4244/EIJV7I6A110⟩. ⟨hal-00812270⟩
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