Neurological Disorders in Primary Sjögren's Syndrome. - Université de Bretagne Occidentale Access content directly
Journal Articles Autoimmune Diseases Year : 2012

Neurological Disorders in Primary Sjögren's Syndrome.

Abstract

Sjögren's syndrome is an autoimmune disease characterized by an autoimmune exocrinopathy involving mainly salivary and lacrimal glands. The histopathological hallmark is periductal lymphocytic infiltration of the exocrine glands, resulting in loss of their secretory function. Several systemic manifestations may be found in patients with Sjögren's syndrome including neurological disorders. Neurological involvement ranges from 0 to 70% among various series and may present with central nervous system and/or peripheral nervous system involvement. This paper endeavors to review the main clinical neurological manifestations in Sjögren syndrome, the physiopathology, and their therapeutic response.

Domains

Immunology
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Dates and versions

hal-00771038 , version 1 (04-02-2016)

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Gabriel J Tobón, Jacques-Olivier Pers, Valérie Devauchelle-Pensec, Pierre Youinou. Neurological Disorders in Primary Sjögren's Syndrome.. Autoimmune Diseases, 2012, 2012, pp.645967. ⟨10.1155/2012/645967⟩. ⟨hal-00771038⟩

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UNIV-BREST IMMUNO
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