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Atrial pacing for prevention of atrial fibrillation: assessment of simultaneously implemented algorithms.

Abstract : AIMS: Several preliminary studies indicated that right atrial pacing could prevent atrial tachyarrhythmias (ATA). We sought to compare the safety and the efficacy of atrial-based pacing supplemented by dedicated combined algorithms with conventional atrial pacing in the prevention of ATA. METHODS: Fifty-five patients with a history of recurrent paroxysmal ATA implanted with a dual-chamber pacemaker were studied during two randomized cross-over pacing periods (conventional DDD and DDD with ATA prevention algorithms) of 6 months duration. The primary endpoint was the burden of ATA episodes recorded by the device mode switch algorithm. RESULTS: The cross-over analysis did not demonstrate any significant difference between the two pacing modes: 254+/-533 h of ATA during the control period versus 238+/-518 h during the ATA prevention period. Analysis of a subgroup of patients found that those with the lower percentage of ventricular pacing benefited from ATA prevention algorithms (120+/-182 h versus 225+/-350 h during the control period; P < 0.04). CONCLUSION: When compared with DDD pacing at 70 bpm, ATA prevention algorithms have not demonstrated significant efficacy. However, a subgroup of patients with preserved native AV conduction (low percentage of ventricular pacing) responded to ATA prevention algorithms.
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Contributor : François Guerrero Connect in order to contact the contributor
Submitted on : Friday, November 9, 2012 - 11:05:40 PM
Last modification on : Saturday, May 21, 2022 - 3:42:42 AM

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Jean-Jacques Blanc, Luc de Roy, Jacques Mansourati, Yann Poezevara, Jean-Louis Marcon, et al.. Atrial pacing for prevention of atrial fibrillation: assessment of simultaneously implemented algorithms.. EP-Europace, Oxford University Press (OUP): Policy B, 2004, 6 (5), pp.371-9. ⟨10.1016/j.eupc.2004.05.002⟩. ⟨hal-00750434⟩



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