Chlamydia pneumoniae IgG serological status and venous thromboembolism: a cross-sectional hospital based study.

Luc De Saint Martin 1, 2, * Elisabeth Pasquier 1, 2 F. Betsou A. Tran 3 Francis Couturaud 1, 2 J. Orfila
* Auteur correspondant
1 GETBO - Groupe d'Etude de la Thrombose de Bretagne Occidentale
2 DMIP - Brest - Département de Médecine Interne et Pneumologie [Brest]
3 CIRAD
Abstract : OBJECTIVE: To search for a link between Chlamydia pneumoniae serological status and venous thromboembolic disease. METHODS: From March 1992 to October 1999, we conducted a cross-sectional hospital-based study of consecutive unselected outpatients referred to us for clinical suspicion of venous thromboembolism. We compared the Chlamydia pneumoniae serological status with respectively, the venous thromboembolism, the deep vein thrombosis and the proximal deep vein thrombosis status. RESULTS: Among 1193 patients registered for suspected venous thromboembolism, 1010 samples were available (499 negative and 511 positive patients for venous thromboembolism). Seventy-nine patients were Chlamydia pneumoniae positive. Our work failed to demonstrate any clear association between Chlamydia pneumoniae and venous thromboembolism status. Nevertheless, we identified a statistical difference regarding Chlamydia pneumoniae seropositivity and proximal vein thrombosis status (adjusted odds ratio of 1.70, CI95%: 1.05 to 2.77). CONCLUSION: The presence of Chlamydia pneumoniae antibodies might be a minor risk factor for venous thrombosis.
Type de document :
Article dans une revue
La Presse medicale, Paris, Masson et Cie, 2004, 33 (21), pp.1493-6
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http://hal.univ-brest.fr/hal-00722254
Contributeur : Ghislaine Calvez <>
Soumis le : mercredi 1 août 2012 - 09:42:13
Dernière modification le : mercredi 10 janvier 2018 - 14:42:02

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  • HAL Id : hal-00722254, version 1
  • PUBMED : 15614169

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CIRAD | GETBO | UNIV-BREST

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Luc De Saint Martin, Elisabeth Pasquier, F. Betsou, A. Tran, Francis Couturaud, et al.. Chlamydia pneumoniae IgG serological status and venous thromboembolism: a cross-sectional hospital based study.. La Presse medicale, Paris, Masson et Cie, 2004, 33 (21), pp.1493-6. 〈hal-00722254〉

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