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Mueller matrix polarimetry for improved liver fibrosis diagnosis

Abstract : An experimental Mueller matrix polarimeter is used to quantify human liver fibrosis by measuring retardance and depolarization of thin biopsies. The former parameter is sensitive to fibrillar collagen, the latter is specifically sensitive to fibrillar collagen around blood vessels, which is not significant for liver fibrosis diagnosis. By using depolarization like a filter, retardance distribution enables to distinguish between disease stages and limit the high degree of observer discrepancy
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https://hal.univ-brest.fr/hal-00680367
Contributor : Matthieu Dubreuil <>
Submitted on : Monday, March 19, 2012 - 12:25:43 PM
Last modification on : Friday, May 17, 2019 - 1:47:32 AM
Long-term archiving on: : Wednesday, June 20, 2012 - 2:25:55 AM

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Matthieu Dubreuil, P. Babilotte, Martin Loïc, David Sevrain, Sylvain Rivet, et al.. Mueller matrix polarimetry for improved liver fibrosis diagnosis. Optics Letters, Optical Society of America, 2012, 37 (6), pp.1061-1063. ⟨10.1364/OL.37.001061⟩. ⟨hal-00680367⟩

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