Characterisation and genetic polymorphism of metallothionein gene CgMT4 in experimental families of Pacific oyster Crassostrea gigas displaying summer mortality

Elise David 1, 2, * Arnaud Tanguy 3, 4 Dario Moraga 1
* Auteur correspondant
1 LEMAR - Laboratoire des Sciences de l'Environnement Marin (LEMAR)
2 Laboratoire d'Eco-Toxicologie
3 ADMM - Adaptation et diversité en milieu marin
4 Génétique et adaptation en Milieu Extrême
Abstract : Summer mortality events have been observed in Pacific oyster Crassostrea gigas for several decades. This paper examines the selective pressure exerted by summer mortality on the polymorphism of a newly identified oyster metallothionein gene. CgMT4 cDNA and genomic sequences were obtained. CgMT4 was studied in two generations of oysters reared in three sites on the French Atlantic coast, using single strand conformation polymorphism analysis. Four alleles were detected. Individuals carrying genotype MT4-CD seem to have higher susceptibility to summer risk conditions. The MT4 gene could be a potential new genetic marker for susceptibility; further validation studies are recommended.
Keywords : Pacific oyster metallothionein susceptibility genotypes selection
Type de document :
Article dans une revue
Biomarkers, Taylor & Francis, 2012, 17 (1), pp.85-95. 〈10.3109/1354750X.2011.639464〉
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http://hal.univ-brest.fr/hal-00679648
Contributeur : Catherine Bertignac <>
Soumis le : vendredi 16 mars 2012 - 09:49:20
Dernière modification le : mercredi 21 mars 2018 - 18:57:46

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Elise David, Arnaud Tanguy, Dario Moraga. Characterisation and genetic polymorphism of metallothionein gene CgMT4 in experimental families of Pacific oyster Crassostrea gigas displaying summer mortality. Biomarkers, Taylor & Francis, 2012, 17 (1), pp.85-95. 〈10.3109/1354750X.2011.639464〉. 〈hal-00679648〉

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