Cardiac multislice spiral computed tomography as an alternative to coronary angiography in the preoperative assessment of coronary artery disease before aortic valve surgery: a management outcome study.

Jean-Christophe Cornily * Martine Gilard 1, 2 Eric Bezon 2 Virginie Jan Pierre-Yves Pennec 3 Yves Etienne 3 Ulric Vinsonneau Grégoire Le Gal 4 Jacques Mansourati 2, 3 Jean-Jacques Blanc 3 Jacques Boschat 2, 3
* Auteur correspondant
1 Service d'Hémodynamique
2 ORPHY (EA 4324) - Optimisation des régulations physiologiques
3 BREST - Cardio - Service de Cardiologie
4 CIC - Brest - Centre d'Investigation Clinique
Abstract : BACKGROUND: Conventional coronary angiography (CA) is still recommended before valvular surgery. Preliminary studies suggest that multislice spiral computed tomography coronary angiography (MSCT-CA) can be used to rule out coronary artery disease (CAD). AIM: To assess prospectively the safety of ruling out CAD before surgery solely on the basis of normal MSCT-CA in patients with severe aortic valve disease. METHODS: We included all consecutive patients scheduled for aortic valve surgery. We first estimated the calcium score (Agatston score equivalent [ASE]). Patients underwent injected MSCT if the ASE was<1000. CA was cancelled when MSCT-CA quality was sufficient and showed no significant CAD. Our primary endpoint was the occurrence of perioperative myocardial infarction in patients who underwent surgery with no prior CA. RESULTS: Between 1st July 2005 and 30th June 2008, we included 199 patients with severe aortic valve disease: 118 men (59%); mean age 69+/-12 years; 63 patients (32%) underwent CA directly because the ASE was > or =1000. Of 136 patients who underwent MSCT-CA, 106 (78%) had a normal MSCT-CA and underwent aortic valve surgery without prior CA; CA was performed in 30 patients because of abnormal (n=18) or bad quality (n=12) MSCT-CA. One patient of the 106 (0.94%, 95% confidence interval 0.17-5.15) had a perioperative myocardial infarction. CONCLUSIONS: When the ASE is <1000, MSCT is safe and may be recommended instead of CA as a first-line means of ruling out CAD in patients with severe aortic valve disease.
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Archives of cardiovascular diseases, Elsevier/French Society of Cardiology, 2010, 103 (3), pp.170-5. 〈10.1016/j.acvd.2010.01.004〉
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http://hal.univ-brest.fr/hal-00678933
Contributeur : Ghislaine Calvez <>
Soumis le : mercredi 14 mars 2012 - 11:41:01
Dernière modification le : jeudi 13 septembre 2018 - 15:17:13

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Jean-Christophe Cornily, Martine Gilard, Eric Bezon, Virginie Jan, Pierre-Yves Pennec, et al.. Cardiac multislice spiral computed tomography as an alternative to coronary angiography in the preoperative assessment of coronary artery disease before aortic valve surgery: a management outcome study.. Archives of cardiovascular diseases, Elsevier/French Society of Cardiology, 2010, 103 (3), pp.170-5. 〈10.1016/j.acvd.2010.01.004〉. 〈hal-00678933〉

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