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Multilayer cell proliferation with an adaptation of cellular Potts model 

S. Tripodi 1 Pascal Ballet 2, * Vincent Rodin 2, *
* Corresponding author
2 Lab-STICC_UBO_CID_IHSEV
Lab-STICC - Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance
Abstract : The cellular Potts model (CPM) is a cellular automaton (CA) for modelling morphogenesis. It characterizes a cell by a volume, a surface and a type. We have extended this model to add the notion of energetic exchange between cells via the secretion and consumption of molecules. These molecules are transformed into energy, allowing the cells to maintain themselves and to divide. To test our adaptation of the CPM we improve the realism of known simulations dealing with embryogenesis. Thanks to the CPM the shape of the cell is more complex than a simple pixel. Our simulation shows multilayer proliferation, similar to the bilayer proliferation described in the literature. In addition it reveals dynamic tissue regeneration, morphogenesis of disjunctive tissues and the dynamic stability of global shape.
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Journal articles
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https://hal.univ-brest.fr/hal-00668648
Contributor : Francoise Jouglas <>
Submitted on : Friday, February 10, 2012 - 10:29:34 AM
Last modification on : Wednesday, June 24, 2020 - 4:19:23 PM

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  • HAL Id : hal-00668648, version 1

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S. Tripodi, Pascal Ballet, Vincent Rodin. Multilayer cell proliferation with an adaptation of cellular Potts model . Journal of Biological Physics and Chemistry, Basel, Switzerland : Collegium Basilea (Institute of Advanced Study) ; Tbilisi : Association of Modern Scientific Investigation (AMSI), 2010, 10 (1), pp.33-38. ⟨hal-00668648⟩

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