Bone marrow fat quantification of osteoporotic vertebral compression fractures: comparison of multi-voxel proton MR spectroscopy and chemical-shift gradient-echo MR imaging.

Abstract : BACKGROUND: Only a few studies have used in/opposed phase method for a quantitative evaluation of fat fraction in the spine. PURPOSE: To compare multivoxel proton MR spectroscopy and chemical-shift gradient-echo MR imaging for bone marrow fat quantification in vertebral compression fractures (VCF). MATERIAL AND METHODS: Vertebral marrow fat quantification in fifteen patients was measured at 3.0-T. Multi-voxel proton spectroscopy (MRS) and in/opposed-phase MR imaging using a fat map build with a triple-echo gradient-echo sequence was used. All the patients had benign vertebral collapse. Bone marrow fat content was evaluated by both techniques in compressed (acute or chronic) and in non-compressed vertebrae. RESULTS: The percentage of fat fraction measured by the triple-echo sequence was well correlated with those calculated by MRS (r(2) = 0.85; P < 10(-4)). There was a significant decrease of fat fraction in acute VCF versus both chronic VCF (P < 10(-9)) and non-fractured vertebrae (P < 10(-7)). There was no significant difference in fat fraction evaluated by both techniques between non-fractured vertebrae and chronic VCF. CONCLUSION: We have validated the in/opposed phase method compared with MRS for vertebral bone marrow fat quantification. The fat mapping using a triple-echo gradient-echo sequence allows distinguishing acute and chronic benign VCF.
Type de document :
Article dans une revue
Acta Radiologica, SAGE Publications, 2011, 52 (9), pp.1032-6. 〈10.1258/ar.2011.100412〉
Liste complète des métadonnées

http://hal.univ-brest.fr/hal-00931370
Contributeur : Ghislaine Calvez <>
Soumis le : mercredi 15 janvier 2014 - 11:52:49
Dernière modification le : mercredi 10 janvier 2018 - 14:42:02

Identifiants

Collections

Citation

Anne Régis-Arnaud, Boris Guiu, Paul-Michael Walker, Denis Krausé, Frédéric Ricolfi, et al.. Bone marrow fat quantification of osteoporotic vertebral compression fractures: comparison of multi-voxel proton MR spectroscopy and chemical-shift gradient-echo MR imaging.. Acta Radiologica, SAGE Publications, 2011, 52 (9), pp.1032-6. 〈10.1258/ar.2011.100412〉. 〈hal-00931370〉

Partager

Métriques

Consultations de la notice

56