Increased thrombin generation measured in the presence of thrombomodulin in women with early pregnancy loss.

Compared with 537 parous controls with no history of pregnancy loss, a lower thrombomodulin-related inhibition of the endogenous thrombin potential was measured in 264 cases with previous unexplained pregnancy loss, especially when losses occurred between 9 and 12 weeks of gestation. Adjusting age, protein S, factor VIII, factor V Leiden, and prothrombin G20210A did not change the results.

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Médecine humaine et pathologie

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https://hal.univ-brest.fr/hal-00721941

Soumis le : mardi 31 juillet 2012-10:30:10

Dernière modification le : mardi 3 octobre 2023-10:38:03

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hal-00721941 , version 1 (31-07-2012)

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HAL Id : hal-00721941 , version 1
DOI : 10.1016/j.fertnstert.2010.11.019
PUBMED : 21130429

Citer

Luc de Saint Martin, Jérôme Duchemin, Caroline Bohec, Francis Couturaud, Dominique Mottier, et al.. Increased thrombin generation measured in the presence of thrombomodulin in women with early pregnancy loss.. Fertility and Sterility, 2011, 95 (5), pp.1813-5.e1. ⟨10.1016/j.fertnstert.2010.11.019⟩. ⟨hal-00721941⟩

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